Difference between revisions of "YMR212C"

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'''Description of YMR212C:''' Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies and is phosphorylated<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000059267'>Lenburg ME and O'Shea EK (2001) Genetic evidence for a morphogenetic function of the Saccharomyces cerevisiae Pho85 cyclin-dependent kinase. Genetics 157(1):39-51 {{SGDpaper|S000059267}} PMID 11139490</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906
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'''Description of YMR212C:''' Protein required for Stt4-containing phosphoinositide kinase patch assembly at the plasma membrane; exhibits synthetic lethal genetic interactions with PHO85; has sequence similarity to the Drosophila rolling blackout (RBO) gene<ref name='S000128684'>Baird D, et al. (2008) Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. J Cell Biol 183(6):1061-74 {{SGDpaper|S000128684}} PMID 19075114</ref><ref name='S000059267'>Lenburg ME and O'Shea EK (2001) Genetic evidence for a morphogenetic function of the Saccharomyces cerevisiae Pho85 cyclin-dependent kinase. Genetics 157(1):39-51
{{SGDpaper|S000123951}} PMID 17761666</ref>
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{{SGDpaper|S000059267}} PMID 11139490</ref>
 
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Revision as of 14:05, 7 June 2010

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Systematic name YMR212C
Gene name EFR3
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:693042..690694
Primary SGDID S000004825


Description of YMR212C: Protein required for Stt4-containing phosphoinositide kinase patch assembly at the plasma membrane; exhibits synthetic lethal genetic interactions with PHO85; has sequence similarity to the Drosophila rolling blackout (RBO) gene[1][2]




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References

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  1. Baird D, et al. (2008) Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. J Cell Biol 183(6):1061-74 SGD PMID 19075114
  2. Lenburg ME and O'Shea EK (2001) Genetic evidence for a morphogenetic function of the Saccharomyces cerevisiae Pho85 cyclin-dependent kinase. Genetics 157(1):39-51 SGD PMID 11139490

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