Difference between revisions of "YLR205C"

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'''Description of YLR205C:''' ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxygenase activity despite similarity to heme oxygenases; expression regulated by AFT1<ref name='S000073085'>Auclair K, et al. (2003) Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae. Protein Expr Purif 28(2):340-9 {{SGDpaper|S000073085}} PMID 12699699</ref><ref name='S000060699'>Foury F and Talibi D (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276(11):7762-8 {{SGDpaper|S000060699}} PMID 11112771</ref><ref name='S000074012'>Protchenko O and Philpott CC (2003) Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae. J Biol Chem 278(38):36582-7
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'''Description of YLR205C:''' ER localized heme oxygenase, involved in the degradation of heme during iron starvation; degradation of intracellular heme may also affect heme-dependent transcription factor activity; expression is regulated by AFT1<ref name='S000073085'>Auclair K, et al. (2003) Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae. Protein Expr Purif 28(2):340-9 {{SGDpaper|S000073085}} PMID 12699699</ref><ref name='S000060699'>Foury F and Talibi D (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276(11):7762-8 {{SGDpaper|S000060699}} PMID 11112771</ref><ref name='S000119917'>Kim D, et al. (2006) Fungal heme oxygenases: Functional expression and characterization of Hmx1 from Saccharomyces cerevisiae and CaHmx1 from Candida albicans. Biochemistry 45(49):14772-80 {{SGDpaper|S000119917}} PMID 17144670</ref><ref name='S000074012'>Protchenko O and Philpott CC (2003) Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae. J Biol Chem 278(38):36582-7
 
  {{SGDpaper|S000074012}} PMID 12840010</ref>
 
  {{SGDpaper|S000074012}} PMID 12840010</ref>
 
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Revision as of 13:05, 12 November 2010

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Systematic name YLR205C
Gene name HMX1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:553679..552726
Primary SGDID S000004195


Description of YLR205C: ER localized heme oxygenase, involved in the degradation of heme during iron starvation; degradation of intracellular heme may also affect heme-dependent transcription factor activity; expression is regulated by AFT1[1][2][3][4]




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References

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  1. Auclair K, et al. (2003) Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae. Protein Expr Purif 28(2):340-9 SGD PMID 12699699
  2. Foury F and Talibi D (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276(11):7762-8 SGD PMID 11112771
  3. Kim D, et al. (2006) Fungal heme oxygenases: Functional expression and characterization of Hmx1 from Saccharomyces cerevisiae and CaHmx1 from Candida albicans. Biochemistry 45(49):14772-80 SGD PMID 17144670
  4. Protchenko O and Philpott CC (2003) Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae. J Biol Chem 278(38):36582-7 SGD PMID 12840010

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