Difference between revisions of "YIL042C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IX:276291..275107
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|nowrap| Chr IX:276292..275108
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001304
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001304

Revision as of 13:05, 3 February 2011

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Systematic name YIL042C
Gene name PKP1
Aliases
Feature type ORF, Verified
Coordinates Chr IX:276292..275108
Primary SGDID S000001304


Description of YIL042C: Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p[1][2]




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References

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  1. Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem 283(15):9759-67 SGD PMID 18180296
  2. Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 SGD PMID 16643908

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