Difference between revisions of "YHR204W"

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'''Description of YHR204W:''' alpha-1,2-specific exomannosidase of the endoplasmic reticulum that generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation<ref name='S000060356'>Jakob CA, et al. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30 {{SGDpaper|S000060356}} PMID 11375935</ref><ref name='S000059976'>Nakatsukasa K, et al. (2001) Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J Biol Chem 276(12):8635-8 {{SGDpaper|S000059976}} PMID 11254655</ref><ref name='S000131763'>Clerc S, et al. (2009) Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol 184(1):159-72
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'''Description of YHR204W:''' alpha-1,2-specific exomannosidase of the endoplasmic reticulum that generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation<ref name='S000131763'>Clerc S, et al. (2009) Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol 184(1):159-72 {{SGDpaper|S000131763}} PMID 19124653</ref><ref name='S000060356'>Jakob CA, et al. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30 {{SGDpaper|S000060356}} PMID 11375935</ref><ref name='S000059976'>Nakatsukasa K, et al. (2001) Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J Biol Chem 276(12):8635-8
{{SGDpaper|S000131763}} PMID 19124653</ref>
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{{SGDpaper|S000059976}} PMID 11254655</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YHR204W
Gene name MNL1
Aliases HTM1
Feature type ORF, Verified
Coordinates Chr VIII:506319..508709
Primary SGDID S000001247


Description of YHR204W: alpha-1,2-specific exomannosidase of the endoplasmic reticulum that generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation[1][2][3]




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References

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  1. Clerc S, et al. (2009) Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol 184(1):159-72 SGD PMID 19124653
  2. Jakob CA, et al. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30 SGD PMID 11375935
  3. Nakatsukasa K, et al. (2001) Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J Biol Chem 276(12):8635-8 SGD PMID 11254655

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