Difference between revisions of "YPR006C"

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=== DNA and RNA Details ===
 
[[Category:Topic:DNA and RNA Details]]
 
==== Other DNA and RNA Details ====
 
[[Category:Topic:DNA and RNA Details:Other DNA and RNA Details]]
 
'''Other Topic''': expression [[Category:Topic:expression]]
 
 
Specifically higher expression in carbon limited chemostat cultures versus carbon excess. <ref name='S000073646'>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 {{SGDpaper|S000073646}} PMID 12414795</ref> <ref name = 'CAset9153-2003-07-25'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9153 Viktor Boer] on 2003-07-25</ref>
 
 
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=== Protein Details ===
 
[[Category:Topic:Protein Details]]
 
==== Other Protein Details ====
 
[[Category:Topic:Protein Details:Other Protein Details]]
 
'''Other Topic''': Regulated by the diauxic shift (glycerol) [[Category:Topic:Regulated by the diauxic shift (glycerol)]]
 
 
Apart from the overall increase in mitochondrial protein mass this protein is induced after the diauxic shift. <ref name='S000074509'>Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 {{SGDpaper|S000074509}} PMID 14597615</ref> <ref name = 'CAset9949-2004-04-08'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9949 Steffen Ohlmeier] on 2004-04-08</ref>
 
 
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==Community Commentary==
 
==Community Commentary==

Revision as of 10:51, 24 January 2007

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Systematic name YPR006C
Gene name ICL2
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:568993..567266
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Description of YPR006C: 2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol[1][2]



Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]


Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart from the overall increase in mitochondrial protein mass this protein is induced after the diauxic shift. [5] [6]


References

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  1. Luttik MA, et al. (2000) The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism. J Bacteriol 182(24):7007-13 SGD PMID 11092862
  2. Heinisch JJ, et al. (1996) Molecular genetics of ICL2, encoding a non-functional isocitrate lyase in Saccharomyces cerevisiae. Yeast 12(13):1285-95 SGD PMID 8923733
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25
  5. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  6. submitted by Steffen Ohlmeier on 2004-04-08

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