Difference between revisions of "YOL025W"
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| − | '''Description of YOL025W:''' Protein involved in the determination of longevity and also in the negative regulation of SCF E3-ubiquitin ligase function; LAG2 is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells<ref name='S000055741'>Childress AM, et al. (1996) LAG2, a gene that determines yeast longevity. Microbiology 142 ( Pt 8):2289-97 {{SGDpaper|S000055741}} PMID 8760941</ref><ref name='S000131589'>Liu Y, et al. (2009) A longevity protein, Lag2, interacts with SCF complex and regulates SCF function. EMBO J | + | '''Description of YOL025W:''' Protein involved in the determination of longevity and also in the negative regulation of SCF E3-ubiquitin ligase function; LAG2 is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells<ref name='S000055741'>Childress AM, et al. (1996) LAG2, a gene that determines yeast longevity. Microbiology 142 ( Pt 8):2289-97 {{SGDpaper|S000055741}} PMID 8760941</ref><ref name='S000131589'>Liu Y, et al. (2009) A longevity protein, Lag2, interacts with SCF complex and regulates SCF function. EMBO J 28(21):3366-77 |
{{SGDpaper|S000131589}} PMID 19763088</ref> | {{SGDpaper|S000131589}} PMID 19763088</ref> | ||
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Revision as of 13:05, 17 November 2009
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| Systematic name | YOL025W |
| Gene name | LAG2 |
| Aliases | ECM36 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:274958..276940 |
| Primary SGDID | S000005385 |
Description of YOL025W: Protein involved in the determination of longevity and also in the negative regulation of SCF E3-ubiquitin ligase function; LAG2 is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells[1][2]
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