Difference between revisions of "YGL003C"
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==Community Commentary== | ==Community Commentary== | ||
Revision as of 11:51, 24 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YGL003C | |
| Gene name | CDH1 | |
| Aliases | HCT1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:494178..492478 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YGL003C: Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of mitotic cyclins resulting in exit from mitosis; targets the APC/C to specific substrates including CDC20, ASE1 and CIN8[1][2]
Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
References
See Help:References on how to add references
- Jump up ↑ Harper JW, et al. (2002) The anaphase-promoting complex: it's not just for mitosis any more. Genes Dev 16(17):2179-206 SGD PMID 12208841
- Jump up ↑ Visintin R, et al. (1997) CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278(5337):460-3 SGD PMID 9334304
- Jump up ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- Jump up ↑ submitted by Jeff Ubersax on 2004-01-27
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