Difference between revisions of "YBR097W"
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| − | '''Description of YBR097W:''' Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p<ref name='S000042062'>Stack JH and Emr SD (1994) Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem 269(50):31552-62 {{SGDpaper|S000042062}} PMID 7989323</ref><ref name='S000052485'>Stack JH, et al. (1995) Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. Annu Rev Cell Dev Biol 11:1-33 {{SGDpaper|S000052485}} PMID 8689553</ref><ref name='S000053384'>Stack JH, et al. (1995) Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol 129(2):321-34 {{SGDpaper|S000053384}} PMID 7721937</ref><ref name='S000117071'>Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 {{SGDpaper|S000117071}} PMID 16839886</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 | + | '''Description of YBR097W:''' Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p<ref name='S000042062'>Stack JH and Emr SD (1994) Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem 269(50):31552-62 {{SGDpaper|S000042062}} PMID 7989323</ref><ref name='S000052485'>Stack JH, et al. (1995) Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. Annu Rev Cell Dev Biol 11():1-33 {{SGDpaper|S000052485}} PMID 8689553</ref><ref name='S000053384'>Stack JH, et al. (1995) Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol 129(2):321-34 {{SGDpaper|S000053384}} PMID 7721937</ref><ref name='S000117071'>Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 {{SGDpaper|S000117071}} PMID 16839886</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 |
{{SGDpaper|S000075100}} PMID 14576278</ref> | {{SGDpaper|S000075100}} PMID 14576278</ref> | ||
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Revision as of 13:05, 18 December 2009
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| Systematic name | YBR097W |
| Gene name | VPS15 |
| Aliases | GRD8, VAC4, VPL19, VPS40 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:436945..441309 |
| Primary SGDID | S000000301 |
Description of YBR097W: Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p[1][2][3][4][5]
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References
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- ↑ Stack JH and Emr SD (1994) Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem 269(50):31552-62 SGD PMID 7989323
- ↑ Stack JH, et al. (1995) Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. Annu Rev Cell Dev Biol 11():1-33 SGD PMID 8689553
- ↑ Stack JH, et al. (1995) Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol 129(2):321-34 SGD PMID 7721937
- ↑ Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 SGD PMID 16839886
- ↑ Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
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