Difference between revisions of "YOR209C"
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| − | '''Description of YOR209C:''' Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus<ref name=' | + | '''Description of YOR209C:''' Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus<ref name='S000070049'>Anderson RM, et al. (2002) Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels. J Biol Chem 277(21):18881-90 {{SGDpaper|S000070049}} PMID 11884393</ref><ref name='S000048730'>Smith JS, et al. (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A 97(12):6658-63 |
| − | {{SGDpaper| | + | {{SGDpaper|S000048730}} PMID 10841563</ref> |
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Revision as of 14:05, 25 February 2010
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| Systematic name | YOR209C |
| Gene name | NPT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:737727..736438 |
| Primary SGDID | S000005735 |
Description of YOR209C: Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus[1][2]
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References
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- ↑ Anderson RM, et al. (2002) Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels. J Biol Chem 277(21):18881-90 SGD PMID 11884393
- ↑ Smith JS, et al. (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A 97(12):6658-63 SGD PMID 10841563
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