Difference between revisions of "YLR233C"
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− | '''Description of YLR233C:''' TLC1 RNA-associated factor involved in telomere length regulation as | + | '''Description of YLR233C:''' TLC1 RNA-associated factor involved in telomere length regulation as recruitment subunit of telomerase; has G-quadruplex promoting activity that is required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA<ref name='S000069751'>Livengood AJ, et al. (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74 {{SGDpaper|S000069751}} PMID 11884619</ref><ref name='S000073607'>Taggart AK and Zakian VA (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80 {{SGDpaper|S000073607}} PMID 12787768</ref><ref name='S000132980'>Zhang ML, et al. (2010) Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Nat Struct Mol Biol 17(2):202-9 |
− | {{SGDpaper| | + | {{SGDpaper|S000132980}} PMID 20098422</ref> |
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Revision as of 14:05, 14 September 2010
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Systematic name | YLR233C |
Gene name | EST1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XII:609526..607427 |
Primary SGDID | S000004223 |
Description of YLR233C: TLC1 RNA-associated factor involved in telomere length regulation as recruitment subunit of telomerase; has G-quadruplex promoting activity that is required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA[1][2][3]
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Contents
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References
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- ↑ Livengood AJ, et al. (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74 SGD PMID 11884619
- ↑ Taggart AK and Zakian VA (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80 SGD PMID 12787768
- ↑ Zhang ML, et al. (2010) Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Nat Struct Mol Biol 17(2):202-9 SGD PMID 20098422
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