Difference between revisions of "YLR128W"
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| − | '''Description of YLR128W:''' | + | '''Description of YLR128W:''' Scaffold-type E3 ligase required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation<ref name='S000082188'>Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61 {{SGDpaper|S000082188}} PMID 15988528</ref><ref name='S000125334'>Kurz T, et al. (2008) Dcn1 functions as a scaffold-type e3 ligase for cullin neddylation. Mol Cell 29(1):23-35 |
| − | {{SGDpaper| | + | {{SGDpaper|S000125334}} PMID 18206966</ref> |
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Revision as of 14:05, 14 January 2010
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| Systematic name | YLR128W |
| Gene name | DCN1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:398531..399434 |
| Primary SGDID | S000004118 |
Description of YLR128W: Scaffold-type E3 ligase required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation[1][2]
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