Difference between revisions of "YLL003W"
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| − | '''Description of YLL003W:''' Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C<ref name='S000052451'>Ma P, et al. (1999) Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G(2) arrest. Yeast 15(11):1097-109 {{SGDpaper|S000052451}} PMID 10455233 | + | '''Description of YLL003W:''' Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C<ref name='S000074049'>Kilmartin JV (2003) Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication. J Cell Biol 162(7):1211-21 {{SGDpaper|S000074049}} PMID 14504268</ref><ref name='S000052451'>Ma P, et al. (1999) Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G(2) arrest. Yeast 15(11):1097-109 |
| − | + | {{SGDpaper|S000052451}} PMID 10455233</ref> | |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YLL003W |
| Gene name | SFI1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:143200..146040 |
| Primary SGDID | S000003926 |
Description of YLL003W: Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C[1][2]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
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References
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- ↑ Kilmartin JV (2003) Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication. J Cell Biol 162(7):1211-21 SGD PMID 14504268
- ↑ Ma P, et al. (1999) Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G(2) arrest. Yeast 15(11):1097-109 SGD PMID 10455233
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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