Difference between revisions of "YGR108W"
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| − | '''Description of YGR108W:''' B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome<ref name='S000044282'>Fitch I, et al. (1992) Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell 3(7):805-18 {{SGDpaper|S000044282}} PMID 1387566 | + | '''Description of YGR108W:''' B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome<ref name='S000044282'>Fitch I, et al. (1992) Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell 3(7):805-18 {{SGDpaper|S000044282}} PMID 1387566</ref><ref name='S000043997'>Ghiara JB, et al. (1991) A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65(1):163-74 {{SGDpaper|S000043997}} PMID 1849458</ref><ref name='S000045432'>Mendenhall MD and Hodge AE (1998) Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1191-243 {{SGDpaper|S000045432}} PMID 9841670</ref><ref name='S000043995'>Surana U, et al. (1991) The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell 65(1):145-61 |
| − | {{SGDpaper| | + | {{SGDpaper|S000043995}} PMID 1849457</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YGR108W |
| Gene name | CLB1 |
| Aliases | SCB1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:703640..705055 |
| Primary SGDID | S000003340 |
Description of YGR108W: B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome[1][2][3][4]
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References
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- ↑ Fitch I, et al. (1992) Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell 3(7):805-18 SGD PMID 1387566
- ↑ Ghiara JB, et al. (1991) A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65(1):163-74 SGD PMID 1849458
- ↑ Mendenhall MD and Hodge AE (1998) Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1191-243 SGD PMID 9841670
- ↑ Surana U, et al. (1991) The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell 65(1):145-61 SGD PMID 1849457
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