Difference between revisions of "YGR075C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:636879..636151
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|nowrap| Chr VII:636875..636147
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003307
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003307

Revision as of 13:05, 3 February 2011

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Systematic name YGR075C
Gene name PRP38
Aliases
Feature type ORF, Verified
Coordinates Chr VII:636875..636147
Primary SGDID S000003307


Description of YGR075C: Unique component of the U4/U6.U5 tri-snRNP particle, required for conformational changes which result in the catalytic activation of the spliceosome; dispensible for spliceosome assembly[1][2]




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References

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  1. Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 SGD PMID 10377396
  2. Xie J, et al. (1998) Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation. EMBO J 17(10):2938-46 SGD PMID 9582287

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