Difference between revisions of "YDR363W"

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'''Description of YDR363W:''' Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins<ref name='S000056456'>Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80 {{SGDpaper|S000056456}} PMID 11090616</ref><ref name='S000071547'>Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 {{SGDpaper|S000071547}} PMID 12399377</ref><ref name='S000080832'>Novatchkova M, et al. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6:22 {{SGDpaper|S000080832}} PMID 15698469</ref><ref name='S000128989'>Mankouri HW, et al. (2009) Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1683-94
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'''Description of YDR363W:''' Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins<ref name='S000056456'>Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80 {{SGDpaper|S000056456}} PMID 11090616</ref><ref name='S000071547'>Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 {{SGDpaper|S000071547}} PMID 12399377</ref><ref name='S000080832'>Novatchkova M, et al. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6():22 {{SGDpaper|S000080832}} PMID 15698469</ref><ref name='S000128989'>Mankouri HW, et al. (2009) Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1683-94
 
  {{SGDpaper|S000128989}} PMID 19158388</ref>
 
  {{SGDpaper|S000128989}} PMID 19158388</ref>
 
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Revision as of 13:05, 18 December 2009

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Systematic name YDR363W
Gene name ESC2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1199176..1200546
Primary SGDID S000002771


Description of YDR363W: Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins[1][2][3][4]




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References

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  1. Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80 SGD PMID 11090616
  2. Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 SGD PMID 12399377
  3. Novatchkova M, et al. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6():22 SGD PMID 15698469
  4. Mankouri HW, et al. (2009) Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1683-94 SGD PMID 19158388

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