Difference between revisions of "YDR280W"

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'''Description of YDR280W:''' Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9)<ref name='S000041327'>Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --&gt; 5' exonucleases. Genes Dev 13(16):2148-58 {{SGDpaper|S000041327}} PMID 10465791</ref><ref name='S000117042'>Synowsky SA, et al. (2006) Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex. Mol Cell Proteomics 5(9):1581-92 {{SGDpaper|S000117042}} PMID 16829593</ref><ref name='S000120270'>Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 {{SGDpaper|S000120270}} PMID 17174896</ref><ref name='S000120282'>Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22
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'''Description of YDR280W:''' Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9)<ref name='S000041327'>Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 {{SGDpaper|S000041327}} PMID 10465791</ref><ref name='S000117042'>Synowsky SA, et al. (2006) Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex. Mol Cell Proteomics 5(9):1581-92 {{SGDpaper|S000117042}} PMID 16829593</ref><ref name='S000120270'>Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 {{SGDpaper|S000120270}} PMID 17174896</ref><ref name='S000120282'>Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22
 
  {{SGDpaper|S000120282}} PMID 17173052</ref>
 
  {{SGDpaper|S000120282}} PMID 17173052</ref>
 
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Revision as of 13:05, 19 December 2009

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Systematic name YDR280W
Gene name RRP45
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1020744..1021661
Primary SGDID S000002688


Description of YDR280W: Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9)[1][2][3][4]




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References

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  1. Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 SGD PMID 10465791
  2. Synowsky SA, et al. (2006) Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex. Mol Cell Proteomics 5(9):1581-92 SGD PMID 16829593
  3. Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 SGD PMID 17174896
  4. Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 SGD PMID 17173052

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