Difference between revisions of "YKL114C"
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| − | '''Description of YKL114C:''' Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine<ref name='S000039558'>Popoff SC, et al. (1990) Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV. Proc Natl Acad Sci U S A 87(11):4193-7 {{SGDpaper|S000039558}} PMID 1693433</ref><ref name='S000054159'>Ramotar D, et al. (1991) Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol Cell Biol 11(9):4537-44 {{SGDpaper|S000054159}} PMID 1715020</ref><ref name='S000082522'>Ishchenko AA, et al. (2005) The 3'- | + | '''Description of YKL114C:''' Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine<ref name='S000039558'>Popoff SC, et al. (1990) Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV. Proc Natl Acad Sci U S A 87(11):4193-7 {{SGDpaper|S000039558}} PMID 1693433</ref><ref name='S000054159'>Ramotar D, et al. (1991) Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol Cell Biol 11(9):4537-44 {{SGDpaper|S000054159}} PMID 1715020</ref><ref name='S000082522'>Ishchenko AA, et al. (2005) The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol 25(15):6380-90 |
{{SGDpaper|S000082522}} PMID 16024777</ref> | {{SGDpaper|S000082522}} PMID 16024777</ref> | ||
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Revision as of 13:05, 19 December 2009
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| Systematic name | YKL114C |
| Gene name | APN1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:224099..222996 |
| Primary SGDID | S000001597 |
Description of YKL114C: Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine[1][2][3]
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References
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- ↑ Popoff SC, et al. (1990) Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV. Proc Natl Acad Sci U S A 87(11):4193-7 SGD PMID 1693433
- ↑ Ramotar D, et al. (1991) Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol Cell Biol 11(9):4537-44 SGD PMID 1715020
- ↑ Ishchenko AA, et al. (2005) The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol 25(15):6380-90 SGD PMID 16024777
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