Difference between revisions of "YIL068C"

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'''Description of YIL068C:''' Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly<ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 {{SGDpaper|S000047160}} PMID 8978675</ref><ref name='S000049442'>TerBush DR and Novick P (1995) Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol 130(2):299-312 {{SGDpaper|S000049442}} PMID 7615633</ref><ref name='S000081798'>Sivaram MV, et al. (2005) Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p. Biochemistry 44(16):6302-11
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'''Description of YIL068C:''' Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly<ref name='S000081798'>Sivaram MV, et al. (2005) Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p. Biochemistry 44(16):6302-11 {{SGDpaper|S000081798}} PMID 15835919</ref><ref name='S000049442'>TerBush DR and Novick P (1995) Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol 130(2):299-312 {{SGDpaper|S000049442}} PMID 7615633</ref><ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94
  {{SGDpaper|S000081798}} PMID 15835919</ref>
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  {{SGDpaper|S000047160}} PMID 8978675</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YIL068C
Gene name SEC6
Aliases
Feature type ORF, Verified
Coordinates Chr IX:235471..233054
Primary SGDID S000001330


Description of YIL068C: Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly[1][2][3]




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References

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  1. Sivaram MV, et al. (2005) Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p. Biochemistry 44(16):6302-11 SGD PMID 15835919
  2. TerBush DR and Novick P (1995) Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol 130(2):299-312 SGD PMID 7615633
  3. TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 SGD PMID 8978675

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