Difference between revisions of "YHR186C"
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| − | '''Description of YHR186C:''' Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors<ref name=' | + | '''Description of YHR186C:''' Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors<ref name='S000072802'>Jacinto E and Hall MN (2003) Tor signalling in bugs, brain and brawn. Nat Rev Mol Cell Biol 4(2):117-26 {{SGDpaper|S000072802}} PMID 12563289</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 {{SGDpaper|S000071528}} PMID 12408816</ref><ref name='S000075967'>Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 {{SGDpaper|S000075967}} PMID 14736892</ref><ref name='S000072891'>Wedaman KP, et al. (2003) Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(3):1204-20 |
{{SGDpaper|S000072891}} PMID 12631735</ref> | {{SGDpaper|S000072891}} PMID 12631735</ref> | ||
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Revision as of 13:05, 25 February 2010
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| Systematic name | YHR186C |
| Gene name | KOG1 |
| Aliases | LAS24 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:480672..475999 |
| Primary SGDID | S000001229 |
Description of YHR186C: Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors[1][2][3][4]
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References
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- ↑ Jacinto E and Hall MN (2003) Tor signalling in bugs, brain and brawn. Nat Rev Mol Cell Biol 4(2):117-26 SGD PMID 12563289
- ↑ Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 SGD PMID 12408816
- ↑ Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 SGD PMID 14736892
- ↑ Wedaman KP, et al. (2003) Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(3):1204-20 SGD PMID 12631735
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