Difference between revisions of "YNL131W"

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'''Description of YNL131W:''' Component of the TOM (translocase of outer mitochondrial membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between TOM and TIM complexes<ref name='S000077460'>Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 {{SGDpaper|S000077460}} PMID 15523480</ref><ref name='S000075327'>Chacinska A, et al. (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22(20):5370-81 {{SGDpaper|S000075327}} PMID 14532110</ref><ref name='S000065447'>Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 {{SGDpaper|S000065447}} PMID 10661891</ref><ref name='S000064135'>Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 {{SGDpaper|S000064135}} PMID 11212341</ref><ref name='S000053146'>van Wilpe S, et al. (1999) Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase. Nature 401(6752):485-9
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'''Description of YNL131W:''' Component of the TOM (translocase of outer mitochondrial membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between TOM and TIM complexes<ref name='S000053146'>van Wilpe S, et al. (1999) Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase. Nature 401(6752):485-9 {{SGDpaper|S000053146}} PMID 10519552</ref><ref name='S000077460'>Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 {{SGDpaper|S000077460}} PMID 15523480</ref><ref name='S000064135'>Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 {{SGDpaper|S000064135}} PMID 11212341</ref><ref name='S000065447'>Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 {{SGDpaper|S000065447}} PMID 10661891</ref><ref name='S000075327'>Chacinska A, et al. (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22(20):5370-81
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Revision as of 13:05, 31 March 2009

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Systematic name YNL131W
Gene name TOM22
Aliases MAS17, MAS22, MOM22
Feature type ORF, Verified
Coordinates Chr XIV:378769..379227
Primary SGDID S000005075


Description of YNL131W: Component of the TOM (translocase of outer mitochondrial membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between TOM and TIM complexes[1][2][3][4][5]




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References

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  1. van Wilpe S, et al. (1999) Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase. Nature 401(6752):485-9 SGD PMID 10519552
  2. Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 SGD PMID 15523480
  3. Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 SGD PMID 11212341
  4. Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 SGD PMID 10661891
  5. Chacinska A, et al. (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22(20):5370-81 SGD PMID 14532110

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