Difference between revisions of "YMR293C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HER2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HER2 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''LRC6''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''GEP6, LRC6''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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'''Description of YMR293C:''' Mitochondrial protein required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; similar to bacterial glutamyl-tRNA amidotransferases; null mutant displays decreased frequency of mitochondrial genome loss<ref name='S000127234'>Federovitch CM, et al. (2008) Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell 19(10):4506-20 {{SGDpaper|S000127234}} PMID 18667535</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
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'''Description of YMR293C:''' Mitochondrial protein required for remodeling of ER caused by Hmg2p overexpression; null has decreased mitochondrial genome loss and decreased cardiolipin and phosphatidylethanolamine levels; like bacterial glutamyl-tRNA amidotransferases<ref name='S000129376'>Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 {{SGDpaper|S000129376}} PMID 19221197</ref><ref name='S000127234'>Federovitch CM, et al. (2008) Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell 19(10):4506-20 {{SGDpaper|S000127234}} PMID 18667535</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
 
  {{SGDpaper|S000071347}} PMID 12140549</ref>
 
  {{SGDpaper|S000071347}} PMID 12140549</ref>
 
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Revision as of 13:05, 9 March 2009

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Systematic name YMR293C
Gene name HER2
Aliases GEP6, LRC6
Feature type ORF, Verified
Coordinates Chr XIII:856792..855398
Primary SGDID S000004907


Description of YMR293C: Mitochondrial protein required for remodeling of ER caused by Hmg2p overexpression; null has decreased mitochondrial genome loss and decreased cardiolipin and phosphatidylethanolamine levels; like bacterial glutamyl-tRNA amidotransferases[1][2][3][4][5]




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References

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  1. Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
  2. Federovitch CM, et al. (2008) Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell 19(10):4506-20 SGD PMID 18667535
  3. Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
  4. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  5. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549

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