Difference between revisions of "YMR116C"

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'''Description of YMR116C:''' G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation<ref name='S000123143'>Zeller CE, et al. (2007) The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast. J Biol Chem 282(34):25168-76 {{SGDpaper|S000123143}} PMID 17591772</ref><ref name='S000077324'>Gerbasi VR, et al. (2004) Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol Cell Biol 24(18):8276-87 {{SGDpaper|S000077324}} PMID 15340087</ref><ref name='S000048202'>Hoffmann B, et al. (1999) The WD protein Cpc2p is required for repression of Gcn4 protein activity in yeast in the absence of amino-acid starvation. Mol Microbiol 31(3):807-22 {{SGDpaper|S000048202}} PMID 10048025</ref><ref name='S000039260'>Chantrel Y, et al. (1998) The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein. Genetics 148(2):559-69
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'''Description of YMR116C:''' G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation<ref name='S000039260'>Chantrel Y, et al. (1998) The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein. Genetics 148(2):559-69 {{SGDpaper|S000039260}} PMID 9504906</ref><ref name='S000048202'>Hoffmann B, et al. (1999) The WD protein Cpc2p is required for repression of Gcn4 protein activity in yeast in the absence of amino-acid starvation. Mol Microbiol 31(3):807-22 {{SGDpaper|S000048202}} PMID 10048025</ref><ref name='S000077324'>Gerbasi VR, et al. (2004) Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol Cell Biol 24(18):8276-87 {{SGDpaper|S000077324}} PMID 15340087</ref><ref name='S000123143'>Zeller CE, et al. (2007) The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast. J Biol Chem 282(34):25168-76
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  {{SGDpaper|S000123143}} PMID 17591772</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YMR116C
Gene name ASC1
Aliases CPC2
Feature type ORF, Verified
Coordinates Chr XIII:500687..499455
Primary SGDID S000004722


Description of YMR116C: G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation[1][2][3][4]




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References

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  1. Chantrel Y, et al. (1998) The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein. Genetics 148(2):559-69 SGD PMID 9504906
  2. Hoffmann B, et al. (1999) The WD protein Cpc2p is required for repression of Gcn4 protein activity in yeast in the absence of amino-acid starvation. Mol Microbiol 31(3):807-22 SGD PMID 10048025
  3. Gerbasi VR, et al. (2004) Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol Cell Biol 24(18):8276-87 SGD PMID 15340087
  4. Zeller CE, et al. (2007) The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast. J Biol Chem 282(34):25168-76 SGD PMID 17591772

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