Difference between revisions of "YER159C"
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| − | '''Description of YER159C:''' Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha<ref name='S000078394'>Cang Y and Prelich G (2002) Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP). Proc Natl Acad Sci U S A 99(20):12727-32 {{SGDpaper|S000078394}} PMID 12237409</ref><ref name='S000073385'>Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 {{SGDpaper|S000073385}} PMID 12686617 | + | '''Description of YER159C:''' Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha<ref name='S000048426'>Kim S, et al. (1997) The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo. Proc Natl Acad Sci U S A 94(3):820-5 {{SGDpaper|S000048426}} PMID 9023340</ref><ref name='S000057997'>Goppelt A and Meisterernst M (1996) Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae. Nucleic Acids Res 24(22):4450-5 {{SGDpaper|S000057997}} PMID 8948634</ref><ref name='S000078394'>Cang Y and Prelich G (2002) Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP). Proc Natl Acad Sci U S A 99(20):12727-32 {{SGDpaper|S000078394}} PMID 12237409</ref><ref name='S000073385'>Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 |
| − | + | {{SGDpaper|S000073385}} PMID 12686617</ref> | |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YER159C |
| Gene name | BUR6 |
| Aliases | NCB1 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:491953..491525 |
| Primary SGDID | S000000961 |
Description of YER159C: Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha[1][2][3][4]
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References
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- ↑ Kim S, et al. (1997) The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo. Proc Natl Acad Sci U S A 94(3):820-5 SGD PMID 9023340
- ↑ Goppelt A and Meisterernst M (1996) Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae. Nucleic Acids Res 24(22):4450-5 SGD PMID 8948634
- ↑ Cang Y and Prelich G (2002) Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP). Proc Natl Acad Sci U S A 99(20):12727-32 SGD PMID 12237409
- ↑ Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 SGD PMID 12686617
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