Difference between revisions of "YEL034W"
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| − | '''Description of YEL034W:''' Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification<ref name=' | + | '''Description of YEL034W:''' Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification<ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 |
| − | {{SGDpaper| | + | {{SGDpaper|S000117998}} PMID 16914118</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YEL034W |
| Gene name | HYP2 |
| Aliases | TIF51A, eIF5A |
| Feature type | ORF, Verified |
| Coordinates | Chr V:85676..86149 |
| Primary SGDID | S000000760 |
Description of YEL034W: Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification[1][2][3]
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References
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- ↑ Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769
- ↑ Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 SGD PMID 11861547
- ↑ Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 SGD PMID 16914118
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