Difference between revisions of "YGL006W"
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− | '''Description of YGL006W:''' Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a<ref name='S000042399'>Marchi V, et al. (1999) Induction of vacuolar Ca2+-ATPase and H+/Ca2+ exchange activity in yeast mutants lacking Pmr1, the Golgi Ca2+-ATPase. FEBS Lett 454(3):181-6 {{SGDpaper|S000042399}} PMID 10431803 | + | '''Description of YGL006W:''' Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a<ref name='S000042898'>Cunningham KW and Fink GR (1994) Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases. J Cell Biol 124(3):351-63 {{SGDpaper|S000042898}} PMID 7507493</ref><ref name='S000042399'>Marchi V, et al. (1999) Induction of vacuolar Ca2+-ATPase and H+/Ca2+ exchange activity in yeast mutants lacking Pmr1, the Golgi Ca2+-ATPase. FEBS Lett 454(3):181-6 |
− | + | {{SGDpaper|S000042399}} PMID 10431803</ref> | |
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Revision as of 13:05, 16 January 2009
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Systematic name | YGL006W |
Gene name | PMC1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:485925..489446 |
Primary SGDID | S000002974 |
Description of YGL006W: Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a[1][2]
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References
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- ↑ Cunningham KW and Fink GR (1994) Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases. J Cell Biol 124(3):351-63 SGD PMID 7507493
- ↑ Marchi V, et al. (1999) Induction of vacuolar Ca2+-ATPase and H+/Ca2+ exchange activity in yeast mutants lacking Pmr1, the Golgi Ca2+-ATPase. FEBS Lett 454(3):181-6 SGD PMID 10431803
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