Difference between revisions of "YDR001C"
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− | '''Description of YDR001C:''' Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p<ref name=' | + | '''Description of YDR001C:''' Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000056060'>Kopp M, et al. (1993) Molecular analysis of the neutral trehalase gene from Saccharomyces cerevisiae. J Biol Chem 268(7):4766-74 {{SGDpaper|S000056060}} PMID 8444853</ref><ref name='S000051465'>Nwaka S, et al. (1995) Expression and function of the trehalase genes NTH1 and YBR0106 in Saccharomyces cerevisiae. J Biol Chem 270(17):10193-8 {{SGDpaper|S000051465}} PMID 7730323</ref><ref name='S000047028'>Zahringer H, et al. (1997) Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein. FEBS Lett 412(3):615-20 |
− | {{SGDpaper| | + | {{SGDpaper|S000047028}} PMID 9276477</ref> |
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Revision as of 14:05, 16 January 2009
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Systematic name | YDR001C |
Gene name | NTH1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:452473..450218 |
Primary SGDID | S000002408 |
Description of YDR001C: Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [5]
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References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Kopp M, et al. (1993) Molecular analysis of the neutral trehalase gene from Saccharomyces cerevisiae. J Biol Chem 268(7):4766-74 SGD PMID 8444853
- ↑ Nwaka S, et al. (1995) Expression and function of the trehalase genes NTH1 and YBR0106 in Saccharomyces cerevisiae. J Biol Chem 270(17):10193-8 SGD PMID 7730323
- ↑ Zahringer H, et al. (1997) Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein. FEBS Lett 412(3):615-20 SGD PMID 9276477
- ↑ submitted by Jeff Ubersax on 2004-01-21
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