Difference between revisions of "YDR519W"
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| − | '''Description of YDR519W:''' Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking<ref name=' | + | '''Description of YDR519W:''' Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking<ref name='S000039323'>Partaledis JA and Berlin V (1993) The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. Proc Natl Acad Sci U S A 90(12):5450-4 {{SGDpaper|S000039323}} PMID 7685904</ref><ref name='S000041004'>Partaledis JA, et al. (1992) Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. Yeast 8(8):673-80 {{SGDpaper|S000041004}} PMID 1279908</ref><ref name='S000047574'>Nielsen JB, et al. (1992) Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. Proc Natl Acad Sci U S A 89(16):7471-5 |
| − | {{SGDpaper| | + | {{SGDpaper|S000047574}} PMID 1380159</ref> |
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Revision as of 03:15, 19 December 2008
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| Systematic name | YDR519W |
| Gene name | FPR2 |
| Aliases | FKB2 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1480418..1480825 |
| Primary SGDID | S000002927 |
Description of YDR519W: Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking[1][2][3]
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References
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- ↑ Partaledis JA and Berlin V (1993) The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. Proc Natl Acad Sci U S A 90(12):5450-4 SGD PMID 7685904
- ↑ Partaledis JA, et al. (1992) Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. Yeast 8(8):673-80 SGD PMID 1279908
- ↑ Nielsen JB, et al. (1992) Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. Proc Natl Acad Sci U S A 89(16):7471-5 SGD PMID 1380159
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