Difference between revisions of "YPR119W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006323 YPR119W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CLB2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CLB2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:771653..773128 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006323 |
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| − | '''Description of | + | '''Description of YPR119W:''' B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome<ref name='S000044282'>Fitch I, et al. (1992) Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell 3(7):805-18 {{SGDpaper|S000044282}} PMID 1387566</ref><ref name='S000043997'>Ghiara JB, et al. (1991) A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65(1):163-74 {{SGDpaper|S000043997}} PMID 1849458</ref><ref name='S000045432'>Mendenhall MD and Hodge AE (1998) Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1191-243 {{SGDpaper|S000045432}} PMID 9841670</ref><ref name='S000043995'>Surana U, et al. (1991) The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell 65(1):145-61 |
{{SGDpaper|S000043995}} PMID 1849457</ref> | {{SGDpaper|S000043995}} PMID 1849457</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | === DNA and RNA Details === | ||
| + | [[Category:Topic:DNA and RNA Details]] | ||
| + | ==== RNA Degradation ==== | ||
| + | [[Category:Topic:DNA and RNA Details:RNA Degradation]] | ||
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| + | mRNA is degraded by RNase MRP <ref name='S000074412'>Gill T, et al. (2004) RNase MRP cleaves the CLB2 mRNA to promote cell cycle progression: novel method of mRNA degradation. Mol Cell Biol 24(3):945-53 {{SGDpaper|S000074412}} PMID 14729943</ref> <ref name = 'CAset5189-2004-04-07'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5189 Mark Schmitt] on 2004-04-07</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPR119W |
| Gene name | CLB2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:771653..773128 |
| Primary SGDID | S000006323 |
Description of YPR119W: B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome[1][2][3][4]
</protect>
Community Commentary
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DNA and RNA Details
RNA Degradation
mRNA is degraded by RNase MRP [5] [6]
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References
See Help:References on how to add references
- ↑ Fitch I, et al. (1992) Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell 3(7):805-18 SGD PMID 1387566
- ↑ Ghiara JB, et al. (1991) A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65(1):163-74 SGD PMID 1849458
- ↑ Mendenhall MD and Hodge AE (1998) Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1191-243 SGD PMID 9841670
- ↑ Surana U, et al. (1991) The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell 65(1):145-61 SGD PMID 1849457
- ↑ Gill T, et al. (2004) RNase MRP cleaves the CLB2 mRNA to promote cell cycle progression: novel method of mRNA degradation. Mol Cell Biol 24(3):945-53 SGD PMID 14729943
- ↑ submitted by Mark Schmitt on 2004-04-07
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