Difference between revisions of "YPR019W"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YPR019W YPR019W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006223 YPR019W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CDC54 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MCM4 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''HCD21, MCM4''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CDC54, HCD21''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:596747..599548
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|nowrap| Chr XVI:596750..599551
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006223
 
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'''Description of {{PAGENAME}}:''' Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p<ref name='S000069529'>Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 {{SGDpaper|S000069529}} PMID 11836525</ref><ref name='S000042473'>Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68():649-86
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'''Description of YPR019W:''' Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p<ref name='S000136716'>Ma X, et al. (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37 {{SGDpaper|S000136716}} PMID 20860810</ref><ref name='S000069529'>Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 {{SGDpaper|S000069529}} PMID 11836525</ref><ref name='S000042473'>Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86
 
  {{SGDpaper|S000042473}} PMID 10872463</ref>
 
  {{SGDpaper|S000042473}} PMID 10872463</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YPR019W
Gene name MCM4
Aliases CDC54, HCD21
Feature type ORF, Verified
Coordinates Chr XVI:596750..599551
Primary SGDID S000006223


Description of YPR019W: Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p[1][2][3]




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Community Commentary

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References

See Help:References on how to add references

  1. Ma X, et al. (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37 SGD PMID 20860810
  2. Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 SGD PMID 11836525
  3. Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 SGD PMID 10872463

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