Difference between revisions of "YNL293W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005237 YNL293W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MSB3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MSB3 '' | ||
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|nowrap| Chr XIV:80640..82541 | |nowrap| Chr XIV:80640..82541 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005237 |
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| − | '''Description of | + | '''Description of YNL293W:''' Rab GTPase-activating protein; regulates endocytosis via activation of Vps21p and Ypt7p; also acts on Ypt52p and Sec4p; also required for proper actin organization; localizes to the plasma membrane and sites of polarized growth, and a portion localizes to endosomes and vacuoles; similar to Msb4p<ref name='S000056405'>Albert S and Gallwitz D (1999) Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition. J Biol Chem 274(47):33186-9 {{SGDpaper|S000056405}} PMID 10559187</ref><ref name='S000048044'>Bach S, et al. (2000) Co-deletion of the MSB3 and MSB4 coding regions affects bipolar budding and perturbs the organization of the actin cytoskeleton. Yeast 16(11):1015-23 {{SGDpaper|S000048044}} PMID 10923023</ref><ref name='S000073833'>Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 {{SGDpaper|S000073833}} PMID 12913108</ref><ref name='S000150869'>Lachmann J, et al. (2012) The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles. Mol Biol Cell 23(13):2516-26 |
| − | {{SGDpaper| | + | {{SGDpaper|S000150869}} PMID 22593206</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 13:05, 13 September 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL293W |
| Gene name | MSB3 |
| Aliases | GYP3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:80640..82541 |
| Primary SGDID | S000005237 |
Description of YNL293W: Rab GTPase-activating protein; regulates endocytosis via activation of Vps21p and Ypt7p; also acts on Ypt52p and Sec4p; also required for proper actin organization; localizes to the plasma membrane and sites of polarized growth, and a portion localizes to endosomes and vacuoles; similar to Msb4p[1][2][3][4]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Albert S and Gallwitz D (1999) Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition. J Biol Chem 274(47):33186-9 SGD PMID 10559187
- ↑ Bach S, et al. (2000) Co-deletion of the MSB3 and MSB4 coding regions affects bipolar budding and perturbs the organization of the actin cytoskeleton. Yeast 16(11):1015-23 SGD PMID 10923023
- ↑ Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 SGD PMID 12913108
- ↑ Lachmann J, et al. (2012) The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles. Mol Biol Cell 23(13):2516-26 SGD PMID 22593206
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