Difference between revisions of "YDR359C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002767 YDR359C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EAF1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EAF1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1194884..1191936 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002767 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002767 | ||
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| − | '''Description of YDR359C:''' Component of the NuA4 histone acetyltransferase complex<ref name='S000073630'>Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 | + | '''Description of YDR359C:''' Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1<ref name='S000125318'>Auger A, et al. (2008) Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants. Mol Cell Biol 28(7):2257-70 {{SGDpaper|S000125318}} PMID 18212047</ref><ref name='S000124986'>Jordan PW, et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222 {{SGDpaper|S000124986}} PMID 18069899</ref><ref name='S000073630'>Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 |
{{SGDpaper|S000073630}} PMID 12672825</ref> | {{SGDpaper|S000073630}} PMID 12672825</ref> | ||
<br> | <br> | ||
Latest revision as of 06:45, 23 January 2012
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| Systematic name | YDR359C |
| Gene name | EAF1 |
| Aliases | VID21 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1194884..1191936 |
| Primary SGDID | S000002767 |
Description of YDR359C: Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1[1][2][3]
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References
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- ↑ Auger A, et al. (2008) Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants. Mol Cell Biol 28(7):2257-70 SGD PMID 18212047
- ↑ Jordan PW, et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222 SGD PMID 18069899
- ↑ Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 SGD PMID 12672825
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