Difference between revisions of "YNL123W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005067 YNL123W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NMA111 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NMA111 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XIV: | + | |nowrap| Chr XIV:394685..397678 |
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− | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005067 |
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− | '''Description of | + | '''Description of YNL123W:''' Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases<ref name='S000114563'>Fahrenkrog B, et al. (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci 117(Pt 1):115-26 {{SGDpaper|S000114563}} PMID 14657274</ref><ref name='S000128102'>Padmanabhan N, et al. (2009) The Yeast HtrA Orthologue Ynm3 Is a Protease with Chaperone Activity that Aids Survival Under Heat Stress. Mol Biol Cell 20(1):68-77 {{SGDpaper|S000128102}} PMID 18946088</ref><ref name='S000114421'>Tong F, et al. (2006) Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis. Mol Genet Genomics 275(4):330-43 {{SGDpaper|S000114421}} PMID 16470384</ref><ref name='S000114909'>Walter D, et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci 119(Pt 9):1843-51 |
− | {{SGDpaper| | + | {{SGDpaper|S000114909}} PMID 16608876</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YNL123W |
Gene name | NMA111 |
Aliases | YNM3 |
Feature type | ORF, Verified |
Coordinates | Chr XIV:394685..397678 |
Primary SGDID | S000005067 |
Description of YNL123W: Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases[1][2][3][4]
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Community Commentary
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References
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- ↑ Fahrenkrog B, et al. (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci 117(Pt 1):115-26 SGD PMID 14657274
- ↑ Padmanabhan N, et al. (2009) The Yeast HtrA Orthologue Ynm3 Is a Protease with Chaperone Activity that Aids Survival Under Heat Stress. Mol Biol Cell 20(1):68-77 SGD PMID 18946088
- ↑ Tong F, et al. (2006) Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis. Mol Genet Genomics 275(4):330-43 SGD PMID 16470384
- ↑ Walter D, et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci 119(Pt 9):1843-51 SGD PMID 16608876
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