Difference between revisions of "YLR386W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004378 YLR386W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VAC14 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VAC14 '' | ||
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|nowrap| Chr XII:893628..896270 | |nowrap| Chr XII:893628..896270 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004378 |
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| − | '''Description of | + | '''Description of YLR386W:''' Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p<ref name='S000069781'>Bonangelino CJ, et al. (2002) Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156(6):1015-28 {{SGDpaper|S000069781}} PMID 11889142</ref><ref name='S000071861'>Dove SK, et al. (2002) Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body. Curr Biol 12(11):885-93 {{SGDpaper|S000071861}} PMID 12062051</ref><ref name='S000074437'>Rudge SA, et al. (2004) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1):24-36 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074437}} PMID 14528018</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR386W |
| Gene name | VAC14 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:893628..896270 |
| Primary SGDID | S000004378 |
Description of YLR386W: Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p[1][2][3]
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References
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- ↑ Bonangelino CJ, et al. (2002) Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156(6):1015-28 SGD PMID 11889142
- ↑ Dove SK, et al. (2002) Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body. Curr Biol 12(11):885-93 SGD PMID 12062051
- ↑ Rudge SA, et al. (2004) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1):24-36 SGD PMID 14528018
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