Difference between revisions of "YIL042C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001304 YIL042C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PKP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PKP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IX: | + | |nowrap| Chr IX:276292..275108 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001304 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001304 | ||
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| − | '''Description of YIL042C:''' Mitochondrial kinase, | + | '''Description of YIL042C:''' Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p<ref name='S000125220'>Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem 283(15):9759-67 {{SGDpaper|S000125220}} PMID 18180296</ref><ref name='S000115275'>Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 |
{{SGDpaper|S000115275}} PMID 16643908</ref> | {{SGDpaper|S000115275}} PMID 16643908</ref> | ||
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YIL042C |
| Gene name | PKP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:276292..275108 |
| Primary SGDID | S000001304 |
Description of YIL042C: Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p[1][2]
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References
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- ↑ Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem 283(15):9759-67 SGD PMID 18180296
- ↑ Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 SGD PMID 16643908
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