Difference between revisions of "YLR233C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR233C YLR233C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004223 YLR233C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''EST1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''EST1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:609526..607427
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|nowrap| Chr XII:609524..607425
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004223
 
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'''Description of {{PAGENAME}}:''' TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere<ref name='S000073607'>Taggart AK and Zakian VA (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80 {{SGDpaper|S000073607}} PMID 12787768</ref><ref name='S000069751'>Livengood AJ, et al. (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74
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'''Description of YLR233C:''' TLC1 RNA-associated factor involved in telomere length regulation as recruitment subunit of telomerase; has G-quadruplex promoting activity that is required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA<ref name='S000069751'>Livengood AJ, et al. (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74 {{SGDpaper|S000069751}} PMID 11884619</ref><ref name='S000073607'>Taggart AK and Zakian VA (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80 {{SGDpaper|S000073607}} PMID 12787768</ref><ref name='S000132980'>Zhang ML, et al. (2010) Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Nat Struct Mol Biol 17(2):202-9
  {{SGDpaper|S000069751}} PMID 11884619</ref>
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  {{SGDpaper|S000132980}} PMID 20098422</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLR233C
Gene name EST1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:609524..607425
Primary SGDID S000004223


Description of YLR233C: TLC1 RNA-associated factor involved in telomere length regulation as recruitment subunit of telomerase; has G-quadruplex promoting activity that is required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA[1][2][3]




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Community Commentary

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References

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  1. Livengood AJ, et al. (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74 SGD PMID 11884619
  2. Taggart AK and Zakian VA (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80 SGD PMID 12787768
  3. Zhang ML, et al. (2010) Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Nat Struct Mol Biol 17(2):202-9 SGD PMID 20098422

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