Difference between revisions of "YLR188W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR188W YLR188W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004178 YLR188W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDL1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDL1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:528302..530389
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|nowrap| Chr XII:528300..530387
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004178
 
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'''Description of {{PAGENAME}}:''' Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress<ref name='S000077413'>Galluhn D and Langer T (2004) Reversible assembly of the ATP-binding cassette transporter Mdl1 with the F1F0-ATP synthase in mitochondria. J Biol Chem 279(37):38338-45 {{SGDpaper|S000077413}} PMID 15247210</ref><ref name='S000073896'>Chloupkova M, et al. (2003) MDL1 is a high copy suppressor of ATM1: evidence for a role in resistance to oxidative stress. J Mol Biol 331(1):155-65 {{SGDpaper|S000073896}} PMID 12875842</ref><ref name='S000060200'>Young L, et al. (2001) Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 291(5511):2135-8 {{SGDpaper|S000060200}} PMID 11251115</ref><ref name='S000042462'>Dean M, et al. (1994) Mapping and sequencing of two yeast genes belonging to the ATP-binding cassette superfamily. Yeast 10(3):377-83
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'''Description of YLR188W:''' Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress<ref name='S000073896'>Chloupkova M, et al. (2003) MDL1 is a high copy suppressor of ATM1: evidence for a role in resistance to oxidative stress. J Mol Biol 331(1):155-65 {{SGDpaper|S000073896}} PMID 12875842</ref><ref name='S000042462'>Dean M, et al. (1994) Mapping and sequencing of two yeast genes belonging to the ATP-binding cassette superfamily. Yeast 10(3):377-83 {{SGDpaper|S000042462}} PMID 7912468</ref><ref name='S000077413'>Galluhn D and Langer T (2004) Reversible assembly of the ATP-binding cassette transporter Mdl1 with the F1F0-ATP synthase in mitochondria. J Biol Chem 279(37):38338-45 {{SGDpaper|S000077413}} PMID 15247210</ref><ref name='S000060200'>Young L, et al. (2001) Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 291(5511):2135-8
  {{SGDpaper|S000042462}} PMID 7912468</ref>
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  {{SGDpaper|S000060200}} PMID 11251115</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YLR188W
Gene name MDL1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:528300..530387
Primary SGDID S000004178


Description of YLR188W: Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress[1][2][3][4]




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Community Commentary

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References

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  1. Chloupkova M, et al. (2003) MDL1 is a high copy suppressor of ATM1: evidence for a role in resistance to oxidative stress. J Mol Biol 331(1):155-65 SGD PMID 12875842
  2. Dean M, et al. (1994) Mapping and sequencing of two yeast genes belonging to the ATP-binding cassette superfamily. Yeast 10(3):377-83 SGD PMID 7912468
  3. Galluhn D and Langer T (2004) Reversible assembly of the ATP-binding cassette transporter Mdl1 with the F1F0-ATP synthase in mitochondria. J Biol Chem 279(37):38338-45 SGD PMID 15247210
  4. Young L, et al. (2001) Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 291(5511):2135-8 SGD PMID 11251115

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