Difference between revisions of "YKR008W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001716 YKR008W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RSC4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RSC4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XI: | + | |nowrap| Chr XI:452201..454078 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001716 |
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| − | '''Description of | + | '''Description of YKR008W:''' Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p<ref name='S000145695'>Charles GM, et al. (2011) Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress. Proc Natl Acad Sci U S A () {{SGDpaper|S000145695}} PMID 21673141</ref><ref name='S000082171'>Kasten M, et al. (2004) Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14. EMBO J 23(6):1348-59 {{SGDpaper|S000082171}} PMID 15014446</ref><ref name='S000061746'>Lorch Y, et al. (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94(1):29-34 {{SGDpaper|S000061746}} PMID 9674424</ref><ref name='S000071685'>Neely KE and Workman JL (2002) The complexity of chromatin remodeling and its links to cancer. Biochim Biophys Acta 1603(1):19-29 {{SGDpaper|S000071685}} PMID 12242108</ref><ref name='S000060439'>Sengupta SM, et al. (2001) The interactions of yeast SWI/SNF and RSC with the nucleosome before and after chromatin remodeling. J Biol Chem 276(16):12636-44 {{SGDpaper|S000060439}} PMID 11304548</ref><ref name='S000124028'>VanDemark AP, et al. (2007) Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol Cell 27(5):817-28 |
| − | {{SGDpaper| | + | {{SGDpaper|S000124028}} PMID 17803945</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKR008W |
| Gene name | RSC4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:452201..454078 |
| Primary SGDID | S000001716 |
Description of YKR008W: Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p[1][2][3][4][5][6]
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Contents
Community Commentary
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References
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- ↑ Charles GM, et al. (2011) Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress. Proc Natl Acad Sci U S A () SGD PMID 21673141
- ↑ Kasten M, et al. (2004) Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14. EMBO J 23(6):1348-59 SGD PMID 15014446
- ↑ Lorch Y, et al. (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94(1):29-34 SGD PMID 9674424
- ↑ Neely KE and Workman JL (2002) The complexity of chromatin remodeling and its links to cancer. Biochim Biophys Acta 1603(1):19-29 SGD PMID 12242108
- ↑ Sengupta SM, et al. (2001) The interactions of yeast SWI/SNF and RSC with the nucleosome before and after chromatin remodeling. J Biol Chem 276(16):12636-44 SGD PMID 11304548
- ↑ VanDemark AP, et al. (2007) Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol Cell 27(5):817-28 SGD PMID 17803945
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