Difference between revisions of "YGL179C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003147 YGL179C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOS3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOS3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:165091..163409 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003147 |
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| − | '''Description of | + | '''Description of YGL179C:''' Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome<ref name='S000086812'>Elbing K, et al. (2006) Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. Biochem J 393(Pt 3):797-805 {{SGDpaper|S000086812}} PMID 16201971</ref><ref name='S000077210'>Hedbacker K, et al. (2004) Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase. Mol Cell Biol 24(18):8255-63 {{SGDpaper|S000077210}} PMID 15340085</ref><ref name='S000073902'>Hong SP, et al. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci U S A 100(15):8839-43 {{SGDpaper|S000073902}} PMID 12847291</ref><ref name='S000073540'>Nath N, et al. (2003) Yeast Pak1 kinase associates with and activates Snf1. Mol Cell Biol 23(11):3909-17 {{SGDpaper|S000073540}} PMID 12748292</ref><ref name='S000073782'>Sutherland CM, et al. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 13(15):1299-305 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073782}} PMID 12906789</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL179C |
| Gene name | TOS3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:165091..163409 |
| Primary SGDID | S000003147 |
Description of YGL179C: Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Elbing K, et al. (2006) Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. Biochem J 393(Pt 3):797-805 SGD PMID 16201971
- ↑ Hedbacker K, et al. (2004) Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase. Mol Cell Biol 24(18):8255-63 SGD PMID 15340085
- ↑ Hong SP, et al. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci U S A 100(15):8839-43 SGD PMID 12847291
- ↑ Nath N, et al. (2003) Yeast Pak1 kinase associates with and activates Snf1. Mol Cell Biol 23(11):3909-17 SGD PMID 12748292
- ↑ Sutherland CM, et al. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 13(15):1299-305 SGD PMID 12906789
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