Difference between revisions of "YFR003C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001899 YFR003C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YPI1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YPI1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VI: | + | |nowrap| Chr VI:153124..152657 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001899 |
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| − | '''Description of | + | '''Description of YFR003C:''' Regulatory subunit of the type I protein phosphatase (PP1) Glc7p; Glc7p participates in the regulation of a variety of metabolic processes including mitosis and glycogen metabolism; in vitro evidence suggests Ypi1p is an inhibitor of Glc7p while in vivo evidence suggests it is an activator; overproduction causes decreased cellular content of glycogen; partial depletion causes lithium sensitivity, while overproduction confers lithium-tolerance<ref name='S000125078'>Bharucha JP, et al. (2008) Ypi1, a Positive Regulator of Nuclear Protein Phosphatase Type 1 Activity in Saccharomyces cerevisiae. Mol Biol Cell 19(3):1032-45 {{SGDpaper|S000125078}} PMID 18172024</ref><ref name='S000074628'>Garcia-Gimeno MA, et al. (2003) Molecular characterization of Ypi1, a novel Saccharomyces cerevisiae type 1 protein phosphatase inhibitor. J Biol Chem 278(48):47744-52 {{SGDpaper|S000074628}} PMID 14506263</ref><ref name='S000148575'>Marquina M, et al. (2012) Modulation of Yeast Alkaline Cation Tolerance by Ypi1 Requires Calcineurin. Genetics () |
| − | {{SGDpaper| | + | {{SGDpaper|S000148575}} PMID 22367039</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 13:05, 3 May 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YFR003C |
| Gene name | YPI1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:153124..152657 |
| Primary SGDID | S000001899 |
Description of YFR003C: Regulatory subunit of the type I protein phosphatase (PP1) Glc7p; Glc7p participates in the regulation of a variety of metabolic processes including mitosis and glycogen metabolism; in vitro evidence suggests Ypi1p is an inhibitor of Glc7p while in vivo evidence suggests it is an activator; overproduction causes decreased cellular content of glycogen; partial depletion causes lithium sensitivity, while overproduction confers lithium-tolerance[1][2][3]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Bharucha JP, et al. (2008) Ypi1, a Positive Regulator of Nuclear Protein Phosphatase Type 1 Activity in Saccharomyces cerevisiae. Mol Biol Cell 19(3):1032-45 SGD PMID 18172024
- ↑ Garcia-Gimeno MA, et al. (2003) Molecular characterization of Ypi1, a novel Saccharomyces cerevisiae type 1 protein phosphatase inhibitor. J Biol Chem 278(48):47744-52 SGD PMID 14506263
- ↑ Marquina M, et al. (2012) Modulation of Yeast Alkaline Cation Tolerance by Ypi1 Requires Calcineurin. Genetics () SGD PMID 22367039
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