Difference between revisions of "YOR090C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005616 YOR090C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PTC5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PTC5 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:492841..491123 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005616 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005616 | ||
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| − | '''Description of YOR090C:''' | + | '''Description of YOR090C:''' Mitochondrial type 2C protein phosphatase (PP2C) involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the serine 133 of the Pda1p subunit; acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p<ref name='S000040841'>Cheng A, et al. (1999) Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases. Genes Dev 13(22):2946-57 {{SGDpaper|S000040841}} PMID 10580002</ref><ref name='S000125220'>Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem 283(15):9759-67 {{SGDpaper|S000125220}} PMID 18180296</ref><ref name='S000115275'>Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 {{SGDpaper|S000115275}} PMID 16643908</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 |
| − | + | {{SGDpaper|S000075100}} PMID 14576278</ref> | |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR090C |
| Gene name | PTC5 |
| Aliases | PPP1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:492841..491123 |
| Primary SGDID | S000005616 |
Description of YOR090C: Mitochondrial type 2C protein phosphatase (PP2C) involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the serine 133 of the Pda1p subunit; acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p[1][2][3][4]
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References
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- ↑ Cheng A, et al. (1999) Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases. Genes Dev 13(22):2946-57 SGD PMID 10580002
- ↑ Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem 283(15):9759-67 SGD PMID 18180296
- ↑ Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 SGD PMID 16643908
- ↑ Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
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