Difference between revisions of "YOR037W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005563 YOR037W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYC2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYC2 '' | ||
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| − | '''Description of YOR037W:''' Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)<ref name=' | + | '''Description of YOR037W:''' Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)<ref name='S000075319'>Bernard DG, et al. (2003) Overlapping specificities of the mitochondrial cytochrome c and c1 heme lyases. J Biol Chem 278(50):49732-42 {{SGDpaper|S000075319}} PMID 14514677</ref><ref name='S000086902'>Bernard DG, et al. (2005) Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. J Biol Chem 280(48):39852-9 {{SGDpaper|S000086902}} PMID 16207709</ref><ref name='S000050483'>Pearce DA, et al. (1998) Cyc2p is required for maintaining ionic stability and efficient cytochrome c import and mitochondrial function in Saccharomyces cerevisiae. FEBS Lett 439(3):307-11 {{SGDpaper|S000050483}} PMID 9845343</ref><ref name='S000061363'>Sanchez NS, et al. (2001) Requirements of Cyc2p and the porin, Por1p, for ionic stability and mitochondrial integrity in Saccharomyces cerevisiae. Arch Biochem Biophys 392(2):326-32 |
| − | {{SGDpaper| | + | {{SGDpaper|S000061363}} PMID 11488609</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR037W |
| Gene name | CYC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:401555..402655 |
| Primary SGDID | S000005563 |
Description of YOR037W: Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Bernard DG, et al. (2003) Overlapping specificities of the mitochondrial cytochrome c and c1 heme lyases. J Biol Chem 278(50):49732-42 SGD PMID 14514677
- ↑ Bernard DG, et al. (2005) Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. J Biol Chem 280(48):39852-9 SGD PMID 16207709
- ↑ Pearce DA, et al. (1998) Cyc2p is required for maintaining ionic stability and efficient cytochrome c import and mitochondrial function in Saccharomyces cerevisiae. FEBS Lett 439(3):307-11 SGD PMID 9845343
- ↑ Sanchez NS, et al. (2001) Requirements of Cyc2p and the porin, Por1p, for ionic stability and mitochondrial integrity in Saccharomyces cerevisiae. Arch Biochem Biophys 392(2):326-32 SGD PMID 11488609
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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