Difference between revisions of "YNL292W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005236 YNL292W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PUS4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PUS4 '' | ||
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− | '''Description of YNL292W:''' Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)<ref name='S000063200'>Qiu H, et al. (2000) Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol 20(7):2505-16 {{SGDpaper|S000063200}} PMID 10713174 | + | '''Description of YNL292W:''' Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)<ref name='S000047525'>Becker HF, et al. (1997) The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi55 in both mitochondrial and cytoplasmic tRNAs. Nucleic Acids Res 25(22):4493-9 {{SGDpaper|S000047525}} PMID 9358157</ref><ref name='S000063200'>Qiu H, et al. (2000) Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol 20(7):2505-16 |
− | + | {{SGDpaper|S000063200}} PMID 10713174</ref> | |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YNL292W |
Gene name | PUS4 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIV:82806..84017 |
Primary SGDID | S000005236 |
Description of YNL292W: Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)[1][2]
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References
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- ↑ Becker HF, et al. (1997) The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi55 in both mitochondrial and cytoplasmic tRNAs. Nucleic Acids Res 25(22):4493-9 SGD PMID 9358157
- ↑ Qiu H, et al. (2000) Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol 20(7):2505-16 SGD PMID 10713174
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