Difference between revisions of "YNL223W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005167 YNL223W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XIV: | + | |nowrap| Chr XIV:227370..228854 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005167 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005167 | ||
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− | '''Description of YNL223W:''' | + | '''Description of YNL223W:''' Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation<ref name='S000059897'>Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 {{SGDpaper|S000059897}} PMID 11038174</ref><ref name='S000120213'>Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 {{SGDpaper|S000120213}} PMID 17204848</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 |
− | {{SGDpaper| | + | {{SGDpaper|S000051835}} PMID 8224160</ref> |
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YNL223W |
Gene name | ATG4 |
Aliases | APG4, AUT2 |
Feature type | ORF, Verified |
Coordinates | Chr XIV:227370..228854 |
Primary SGDID | S000005167 |
Description of YNL223W: Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation[1][2][3]
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Contents
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References
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- ↑ Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 SGD PMID 11038174
- ↑ Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 SGD PMID 17204848
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
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