Difference between revisions of "YGL043W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003011 YGL043W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003011 YGL043W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DST1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DST1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:417487..418416
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|nowrap| Chr VII:417483..418412
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003011
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003011
 
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'''Description of YGL043W:''' General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites<ref name='S000072763'>Ubukata T, et al. (2003) Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. J Biol Chem 278(10):8580-5 {{SGDpaper|S000072763}} PMID 12496271</ref><ref name='S000062755'>Olmsted VK, et al. (1998) Yeast transcript elongation factor (TFIIS), structure and function. I: NMR structural analysis of the minimal transcriptionally active region. J Biol Chem 273(35):22589-94 {{SGDpaper|S000062755}} PMID 9712887</ref><ref name='S000052904'>Wu J, et al. (1996) In vitro characterization of mutant yeast RNA polymerase II with reduced binding for elongation factor TFIIS. Proc Natl Acad Sci U S A 93(21):11552-7 {{SGDpaper|S000052904}} PMID 8876173</ref><ref name='S000045304'>Davie JK and Kane CM (2000) Genetic interactions between TFIIS and the Swi-Snf chromatin-remodeling complex. Mol Cell Biol 20(16):5960-73
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'''Description of YGL043W:''' General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress<ref name='S000045304'>Davie JK and Kane CM (2000) Genetic interactions between TFIIS and the Swi-Snf chromatin-remodeling complex. Mol Cell Biol 20(16):5960-73 {{SGDpaper|S000045304}} PMID 10913179</ref><ref name='S000150802'>Gomez-Herreros F, et al. (2012) TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress. Nucleic Acids Res 40(14):6508-19 {{SGDpaper|S000150802}} PMID 22544605</ref><ref name='S000062755'>Olmsted VK, et al. (1998) Yeast transcript elongation factor (TFIIS), structure and function. I: NMR structural analysis of the minimal transcriptionally active region. J Biol Chem 273(35):22589-94 {{SGDpaper|S000062755}} PMID 9712887</ref><ref name='S000072763'>Ubukata T, et al. (2003) Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. J Biol Chem 278(10):8580-5 {{SGDpaper|S000072763}} PMID 12496271</ref><ref name='S000052904'>Wu J, et al. (1996) In vitro characterization of mutant yeast RNA polymerase II with reduced binding for elongation factor TFIIS. Proc Natl Acad Sci U S A 93(21):11552-7
{{SGDpaper|S000045304}} PMID 10913179</ref>
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{{SGDpaper|S000052904}} PMID 8876173</ref>
 
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Latest revision as of 13:05, 12 September 2012

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Systematic name YGL043W
Gene name DST1
Aliases PPR2
Feature type ORF, Verified
Coordinates Chr VII:417483..418412
Primary SGDID S000003011


Description of YGL043W: General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress[1][2][3][4][5]




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References

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  1. Davie JK and Kane CM (2000) Genetic interactions between TFIIS and the Swi-Snf chromatin-remodeling complex. Mol Cell Biol 20(16):5960-73 SGD PMID 10913179
  2. Gomez-Herreros F, et al. (2012) TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress. Nucleic Acids Res 40(14):6508-19 SGD PMID 22544605
  3. Olmsted VK, et al. (1998) Yeast transcript elongation factor (TFIIS), structure and function. I: NMR structural analysis of the minimal transcriptionally active region. J Biol Chem 273(35):22589-94 SGD PMID 9712887
  4. Ubukata T, et al. (2003) Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. J Biol Chem 278(10):8580-5 SGD PMID 12496271
  5. Wu J, et al. (1996) In vitro characterization of mutant yeast RNA polymerase II with reduced binding for elongation factor TFIIS. Proc Natl Acad Sci U S A 93(21):11552-7 SGD PMID 8876173

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