Difference between revisions of "YER018C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YER018C YER018C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000820 YER018C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPC25 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPC25 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:192623..191958
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|nowrap| Chr V:192624..191959
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000820
 
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'''Description of {{PAGENAME}}:''' Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering<ref name='S000080960'>He X, et al. (2001) Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell 106(2):195-206 {{SGDpaper|S000080960}} PMID 11511347</ref><ref name='S000062011'>Janke C, et al. (2001) The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J 20(4):777-91 {{SGDpaper|S000062011}} PMID 11179222</ref><ref name='S000059963'>Wigge PA and Kilmartin JV (2001) The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J Cell Biol 152(2):349-60
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'''Description of YER018C:''' Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering<ref name='S000080960'>He X, et al. (2001) Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell 106(2):195-206 {{SGDpaper|S000080960}} PMID 11511347</ref><ref name='S000062011'>Janke C, et al. (2001) The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J 20(4):777-91 {{SGDpaper|S000062011}} PMID 11179222</ref><ref name='S000059963'>Wigge PA and Kilmartin JV (2001) The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J Cell Biol 152(2):349-60
 
  {{SGDpaper|S000059963}} PMID 11266451</ref>
 
  {{SGDpaper|S000059963}} PMID 11266451</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YER018C
Gene name SPC25
Aliases
Feature type ORF, Verified
Coordinates Chr V:192624..191959
Primary SGDID S000000820


Description of YER018C: Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering[1][2][3]




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References

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  1. He X, et al. (2001) Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell 106(2):195-206 SGD PMID 11511347
  2. Janke C, et al. (2001) The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J 20(4):777-91 SGD PMID 11179222
  3. Wigge PA and Kilmartin JV (2001) The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J Cell Biol 152(2):349-60 SGD PMID 11266451

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