Difference between revisions of "YDR495C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002903 YDR495C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1441150..1438115 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002903 |
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| − | '''Description of | + | '''Description of YDR495C:''' Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase<ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 {{SGDpaper|S000122612}} PMID 17488625</ref><ref name='S000047885'>Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 {{SGDpaper|S000047885}} PMID 2202738</ref><ref name='S000045321'>Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 {{SGDpaper|S000045321}} PMID 3062374</ref><ref name='S000039392'>Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100 |
{{SGDpaper|S000039392}} PMID 2526133</ref> | {{SGDpaper|S000039392}} PMID 2526133</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR495C |
| Gene name | VPS3 |
| Aliases | PEP6, VPL3, VPT17 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1441150..1438115 |
| Primary SGDID | S000002903 |
Description of YDR495C: Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase[1][2][3][4]
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Community Commentary
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References
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- ↑ Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625
- ↑ Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 SGD PMID 2202738
- ↑ Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 SGD PMID 3062374
- ↑ Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100 SGD PMID 2526133
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