Difference between revisions of "YOR260W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005786 YOR260W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GCD1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GCD1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:813984..815720 | |nowrap| Chr XV:813984..815720 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005786 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YOR260W:''' Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression<ref name='S000066074'>Hinnebusch A (1992) General and Pathway-specific Regulatory Mechanisms Controlling the Synthesis of Amino Acid Biosynthetic Enzymes in Saccharomyces cerevisiae. Pp. 319-414 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000066074}} PMID </ref><ref name='S000048920'>Pavitt GD, et al. (1998) eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Genes Dev 12(4):514-26 |
{{SGDpaper|S000048920}} PMID 9472020</ref> | {{SGDpaper|S000048920}} PMID 9472020</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR260W |
| Gene name | GCD1 |
| Aliases | TRA3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:813984..815720 |
| Primary SGDID | S000005786 |
Description of YOR260W: Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression[1][2]
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References
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- ↑ Hinnebusch A (1992) General and Pathway-specific Regulatory Mechanisms Controlling the Synthesis of Amino Acid Biosynthetic Enzymes in Saccharomyces cerevisiae. Pp. 319-414 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
- ↑ Pavitt GD, et al. (1998) eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Genes Dev 12(4):514-26 SGD PMID 9472020
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