Difference between revisions of "YDR110W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR110W YDR110W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002517 YDR110W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''FOB1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''FOB1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:676099..677799
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|nowrap| Chr IV:676102..677802
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002517
 
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'''Description of {{PAGENAME}}:''' Nucleolar protein required for DNA replication fork blocking and recombinational hotspot activities; binds to the replication fork barrier site in the rDNA region; related to retroviral integrases<ref name='S000075098'>Kobayashi T (2003) The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork. Mol Cell Biol 23(24):9178-88 {{SGDpaper|S000075098}} PMID 14645529</ref><ref name='S000069930'>Dlakic M (2002) A model of the replication fork blocking protein Fob1p based on the catalytic core domain of retroviral integrases. Protein Sci 11(5):1274-7 {{SGDpaper|S000069930}} PMID 11967383</ref><ref name='S000056096'>Kobayashi T and Horiuchi T (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1(5):465-74 {{SGDpaper|S000056096}} PMID 9078378</ref><ref name='S000044333'>Defossez PA, et al. (1999) Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol Cell 3(4):447-55
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'''Description of YDR110W:''' Nucleolar protein that binds the rDNA replication fork barrier (RFB) site; required for replication fork blocking, recombinational hotspot activity, condensin recruitment to RFB and rDNA repeat segregation; related to retroviral integrases<ref name='S000044333'>Defossez PA, et al. (1999) Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol Cell 3(4):447-55 {{SGDpaper|S000044333}} PMID 10230397</ref><ref name='S000069930'>Dlakic M (2002) A model of the replication fork blocking protein Fob1p based on the catalytic core domain of retroviral integrases. Protein Sci 11(5):1274-7 {{SGDpaper|S000069930}} PMID 11967383</ref><ref name='S000129985'>Johzuka K and Horiuchi T (2009) The cis element and factors required for condensin recruitment to chromosomes. Mol Cell 34(1):26-35 {{SGDpaper|S000129985}} PMID 19362534</ref><ref name='S000075098'>Kobayashi T (2003) The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork. Mol Cell Biol 23(24):9178-88 {{SGDpaper|S000075098}} PMID 14645529</ref><ref name='S000056096'>Kobayashi T and Horiuchi T (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1(5):465-74
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  {{SGDpaper|S000056096}} PMID 9078378</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDR110W
Gene name FOB1
Aliases HRM1
Feature type ORF, Verified
Coordinates Chr IV:676102..677802
Primary SGDID S000002517


Description of YDR110W: Nucleolar protein that binds the rDNA replication fork barrier (RFB) site; required for replication fork blocking, recombinational hotspot activity, condensin recruitment to RFB and rDNA repeat segregation; related to retroviral integrases[1][2][3][4][5]




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References

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  1. Defossez PA, et al. (1999) Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol Cell 3(4):447-55 SGD PMID 10230397
  2. Dlakic M (2002) A model of the replication fork blocking protein Fob1p based on the catalytic core domain of retroviral integrases. Protein Sci 11(5):1274-7 SGD PMID 11967383
  3. Johzuka K and Horiuchi T (2009) The cis element and factors required for condensin recruitment to chromosomes. Mol Cell 34(1):26-35 SGD PMID 19362534
  4. Kobayashi T (2003) The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork. Mol Cell Biol 23(24):9178-88 SGD PMID 14645529
  5. Kobayashi T and Horiuchi T (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1(5):465-74 SGD PMID 9078378

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