Difference between revisions of "YGL003C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002971 YGL003C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CDH1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CDH1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:494174..492474 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002971 | ||
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| − | '''Description of | + | '''Description of YGL003C:''' Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p<ref name='S000071457'>Harper JW, et al. (2002) The anaphase-promoting complex: it's not just for mitosis any more. Genes Dev 16(17):2179-206 {{SGDpaper|S000071457}} PMID 12208841</ref><ref name='S000052656'>Visintin R, et al. (1997) CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278(5337):460-3 {{SGDpaper|S000052656}} PMID 9334304</ref><ref name='S000120283'>Woodbury EL and Morgan DO (2007) Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase. Nat Cell Biol 9(1):106-12 |
| − | {{SGDpaper| | + | {{SGDpaper|S000120283}} PMID 17173039</ref> |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL003C |
| Gene name | CDH1 |
| Aliases | HCT1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:494174..492474 |
| Primary SGDID | S000002971 |
Description of YGL003C: Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
See Help:References on how to add references
- Jump up ↑ Harper JW, et al. (2002) The anaphase-promoting complex: it's not just for mitosis any more. Genes Dev 16(17):2179-206 SGD PMID 12208841
- Jump up ↑ Visintin R, et al. (1997) CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278(5337):460-3 SGD PMID 9334304
- Jump up ↑ Woodbury EL and Morgan DO (2007) Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase. Nat Cell Biol 9(1):106-12 SGD PMID 17173039
- Jump up ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- Jump up ↑ submitted by Jeff Ubersax on 2004-01-27
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