Difference between revisions of "YPR024W"
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− | '''Description of YPR024W:''' Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover<ref name='S000051105'>Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 {{SGDpaper|S000051105}} PMID 9683639</ref><ref name='S000113568'>Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 {{SGDpaper|S000113568}} PMID 16267274</ref><ref name='S000061539'>Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 {{SGDpaper|S000061539}} PMID 10192337</ref><ref name='S000047590'>Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 | + | '''Description of YPR024W:''' Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; also has a role in intermembrane space protein folding; mutation causes an elevated rate of mitochondrial turnover<ref name='S000051105'>Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 {{SGDpaper|S000051105}} PMID 9683639</ref><ref name='S000113568'>Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 {{SGDpaper|S000113568}} PMID 16267274</ref><ref name='S000061539'>Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 {{SGDpaper|S000061539}} PMID 10192337</ref><ref name='S000151061'>Schreiner B, et al. (2012) Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria. Mol Biol Cell () {{SGDpaper|S000151061}} PMID 22993211</ref><ref name='S000047590'>Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 |
{{SGDpaper|S000047590}} PMID 8514129</ref> | {{SGDpaper|S000047590}} PMID 8514129</ref> | ||
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Latest revision as of 14:05, 5 October 2012
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Systematic name | YPR024W |
Gene name | YME1 |
Aliases | OSD1, YTA11 |
Feature type | ORF, Verified |
Coordinates | Chr XVI:610481..612724 |
Primary SGDID | S000006228 |
Description of YPR024W: Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; also has a role in intermembrane space protein folding; mutation causes an elevated rate of mitochondrial turnover[1][2][3][4][5]
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References
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- ↑ Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 SGD PMID 9683639
- ↑ Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
- ↑ Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 SGD PMID 10192337
- ↑ Schreiner B, et al. (2012) Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria. Mol Biol Cell () SGD PMID 22993211
- ↑ Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 SGD PMID 8514129
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